Acute lung injury (ALI) leading to acute respiratory distress syndrome (ARDS) is a critical clinical condition characterized by increased pulmonary permeability and respiratory distress following severe infection, trauma, or shock. This disease, caused by various severe non-cardiac factors, manifests as acute, progressively worsening dyspnea and refractory hypoxemia, with a mortality rate as high as 30%. The novel coronavirus pneumonia currently ravaging the globe frequently progresses to ARDS i

BALB/C Mouse (female, 8 weeks old)
Model creation method: LPS solution nebulization inhalation to establish an acute lung injury model.
Positive drug: Methylprednisolone tablets
Evaluation Criteria: ELISA, Hematoxylin and Eosin (HE) staining

肺泡灌洗液ELISA

肺组织HE染色